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CNS Demyelinating Disease Pathology, Especially Neuropathology

Our featured speaker today is Dr. Douglas C. Miller.

Douglas C Miller is currently Clinical Professor in the Department of Pathology & Anatomical Sciences of the University of Missouri School of Medicine in Columbia, MO.  Dr Miller is a native of New York City, did his undergraduate studies at Williams College and got his MD degree at the University of Miami School of Medicine in 1978.  He stayed in Miami to complete his PhD work, earning that degree in the Department of Physiology & Biophysics in 1980.  He did his residencies at the Massachusetts General Hospital and Harvard Medical School (Anatomic Pathology 1980-82; Neuropathology 1982-84).  He is certified in Anatomic Pathology and Neuropathology by the American Board of Pathology.


Dr Miller has been full-time faculty first at the UMDNJ-Robert Wood Johnson Medical School (Assistant Professor of Pathology, 1984-87), and then at New York University School of Medicine (Assistant Professor of Pathology and Neurosurgery, 1987-1994; Associate Professor of Neuropathology & Neurosurgery 1994-2002; Professor of Neuropathology & Neurosurgery, 2002-2007), before moving to Missouri and assuming his current appointment.  Dr Miller has published extensively (over 140 papers and chapters) in several areas of neuropathology, mostly concerning primary brain tumors but also neurodegenerative diseases and infectious and inflammatory disorders.  He has always taught and emphasized the importance of correlations between clinical data, neuroimaging data, and neuropathology: for example he was co-author on one of the earliest studies of MR imaging correlated with neuropathological findings, and he established that the pathological basis of the movement disorder in a large kindred with familial parkinsonism was actually Parkinson’s Disease, a finding which led to the discovery that Lewy Bodies were largely composed of alpha-synuclein.

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