Hematopathology Services
Patients. Results. Answers.
Hematopathology Diagnostic Services
Our hematology services include a full range of pathology expertise and advanced laboratory diagnostics. Pediatric and adult patients with benign and malignant hematolymphoid disorders can benefit from our subspecialty services that provide accurate and timely diagnoses, assist with prognostic stratification, and guide therapy selection and monitoring.

As a leading provider of state-of-the-art laboratory diagnostics required in modern hematology practice, our menu of services is complemented by a solid foundation of expert consultation for bone marrow biopsies and lymphoid tissues.
We are able to provide data necessary to answer today's complex hematology questions through our robust offerings in flow cytometry, molecular hematology, immunohistochemistry and cytogenetics, as well as interpretation of that data by highly trained hematopathologists who add context to the results.

From performing a single test to providing full-service consultations, we offer a spectrum of services tailored to the needs of each client.
  • Composed of plasma (55%) and blood cells (45%)
  • Responsible for transport of oxygen, carbon dioxide, nutrients, cell waste, antibodies, and immune cells
  • Completes circulatory loop in 20 seconds
  • Adults have 6 liters of blood containing 35 trillion cells
Heme tissues
1.Blood:
  • Organ of T-cell production found anterosuperior to heart
  • Grows from 20 to 35 grams into teens, and progressively disappears ("involutes") in adulthood
  • Responsible for producing T-cells for cellular immunity
2.Thymus:
  • Multifunctional organ that houses hematopoiesis in utero
  • Found in upper right abdominal quadrant
  • 1200-1500 grams
  • Responsible for blood cell production in utero and supplemental blood filtration
3. Liver:
  • An organized collection of immune cells
  • Responsible for immunity
  • Adults have 800 lymph nodes and their size is quite variable
4.Lymph Node:
  • Two large lymph node-like organs in oral cavity pillars
  • Each measure on average 2.5 - 3 cm in dimension
  • Responsible for immune surveillance
5.Tonsils:
  • Blood filter found in upper left abdominal quadrant
  • 12 cm in largest diameter and 150-200 grams
  • Contains red blood cell "obstacle course" and many lymph node-like immune cell collections
  • Responsible for clearing old red blood cells and immunity
6.Spleen:
  • Composed of hematopoietic cells and fat
  • Produces 2.5 million cells/second
  • Found in all bones at birth, but recedes to axial bones (pelvis, vertebra, and ribs) with age
  • Responsible for producing blood and immune cells, and maintaining the genome
  • Adults have 2 liters of bone marrow containing 2 trillion cells
  • Humans have 22,000 stem cells at birth
7.Bone Marrow:
5 tests in 1 lab
The appearance of cells and their relationship to one another under the microscope is the cornerstone of pathology. When abnormal cell proliferations arise, identification of the cell of origin is vital for proper disease classification and management. Cells may have a wide variety of morphologies, and their sizes, shapes, colors, nuclear and cytoplasmic features, and the company they keep often disclose their origin.

Utilizing many different histological stains, including routine stains (H&E and Wright-Giemsa), special stains (iron, trichrome, Congo Red, etc.), and immunohistochemical stains (AE1/AE3, SOX11, CD45RB, etc.), cell features can be accentuated to improve their characterization. Microscopy allows for the visual evaluation of thousands of cells, and at GoPath, our experienced eyes and extensive stain menu (>120 stains) translate into timely, accurate diagnoses.
The leading choice of pathologists, clinicians and patients who seek an expert opinion in hematopathology
GoPath Diagnostics offers physicians an unsurpassed level of expertise, state-of-the-art scientific analysis and personal attention. Guided by the vision and leadership of Dr. Jim Lu and Dr. David Wilson, we offer referring physicians the speed and accuracy of results required to best assist their patients.

With our full-service consultative services, we provide a single, comprehensive hematopathology consultation report containing detailed diagnostic and prognostic information. For patients with multiple samples, a systematic comparative evaluation is used to address issues such as disease progression and response to therapy. This approach is critical in view of the complicated diagnostic algorithms necessary to apply the current WHO (2022) criteria, especially in cases of organ-based lymphomas, lymphomas in immunocompromised patients, and in many myeloid neoplasms. Telephone consultations are encouraged and a dialogue with the clinician may even be necessary to reach a comprehensive interpretation and to understand the full implications of the diagnosis.
Referring physicians and their patients benefit from:
Consultation and case review by international experts in hematopathology—difficult cases are discussed in a consensus conference. Clients benefit from the expertise of five hematopathologists without incurring additional fees.

State-of-the-art flow cytometry, immunohistochemistry
and molecular laboratories.

Efficient personal attention and timely reporting.

Specimen shipping at no cost to the physician or patient. For consultation cases, all tissue block(s) and original slides are promptly returned.
Sample report
1.Final Diagnosis
Determined through comprehensive assessment of all tests performed
2.Morphology
Cytologic and histologic evaluation of cells and tissue by microscopy
3.Flow Cytometry
Immunophenotypic characterization of all cell populations
4.Cytogenetics
Analysis of number and structure of chromosomes
5.FISH
Identification of specific genetic abnormalities using fluorescent-labeled probes
6.Molecular
Single or multiple gene sequencing to identify genomic aberrations
David Wilson, M D
Director of Hematopathology
Education
Indiana University School of Medicine
Experience
Over 21 years reading +2,500 bone marrow cases
Dr. Wilson earned his medical degree and completed his residency in Clinical and Anatomic Pathology, and his fellowship in Hematopathology at the Indiana University School of Medicine. Dr. Wilson is a Chairman of the Department of Pathology at St. Vincent Hospital and a Hematology and Blood Bank instructor at Marion University College of Osteopathic Medicine. He is a member of several societies, including the College of American Pathology (CAP), the Society for Hematopathology, and the United States and Canadian Academy of Pathologists (USCAP). Dr. Wilson has been published in the American Journal of Clinical Pathology and the ACC Current Journal.

Dr. Wilson has practiced hematopathology and surgical pathology for more than 20 years in Indianapolis, where under his direction, he grew a small local hematology laboratory into a busy midwestern Hematopathology Service that has averaged more than 7,000 blood smear reviews, 2,000 bone marrows, 5,000 flow cytometry cases, 5,000 heme-related surgicals, and 6,000 coagulation consults per year.
As a frequent and active participant in annual international pathology and clinical hematology conferences, Dr. Wilson has maintained this state-of-the-art service in an increasingly complex hematopathology landscape.

To the clinicians he has served, Dr. Wilson is well known for his sense of humor, tireless work ethic, efficiency, accessibility, staunch patient advocacy, timeliness, and mastery.
Hematology Diagnostic Services
We're world-class
Providing our clients with world-class hematology diagnostics and laboratory medicine services is our passion. The Department of Hematopathology delivers total customer satisfaction with its quick turnaround time, friendly Client Services department, and on-time billing.
5 tests in 1 lab
GoPoiesis
5-7 days
3-4 days
Integrated Heme Report
24-48 hours
12-24 hours
Turnaround Times
90 min.
Microscopy
Flow Cytometry
FISH
Molecular
Cytogenetics
The story of our full-service diagnostics laboratory begins with