Blood cancer occurs when malignant cells form in the tissues of the breast.
Understanding blood cancer
Cancer can start almost anywhere in the body, affecting tissues, organs, and systems in different ways. Better outcomes begin with early detection and individualized care.
Types of blood cancers
Leukemia
Leukemia is a type of cancer that starts in the blood-forming tissues, primarily the bone marrow and lymphatic system.
Lymphoma
ChatGPT said: Lymphoma is a type of cancer that begins in the lymphatic system—a key part of the immune system that includes lymph nodes, spleen, thymus, and bone marrow.
Multiple myeloma
Multiple myeloma is a type of blood cancer that develops in plasma cells, a type of white blood cell found in the bone marrow that normally produces antibodies to fight infection.
Myelodysplastic syndromes (MDS)
Myelodysplastic syndromes (MDS) are a group of disorders in which the bone marrow does not produce enough healthy blood cells.
Common symptoms
A lump or thickening in the breast or underarm that feels different from surrounding tissue
Change in breast size, shape, or appearance, including swelling or visible distortion
Skin changes on the breast, such as dimpling, puckering, redness, or scaling
Nipple changes, such as inversion (turning inward), pain, or discharge (especially bloody or clear)
Persistent breast pain or tenderness not linked to the menstrual cycle
Changes in skin texture resembling an orange peel (peau d’orange)
Testings options in our lab
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Complete Blood Count (CBC) – Measures red cells, white cells, platelets; abnormalities may suggest leukemia, MDS, or other blood disorders.
Peripheral Blood Smear – Microscopic examination of blood cells for size, shape, and maturity.
Blood Chemistry Panel – Checks organ function (kidney, liver), calcium levels (important in multiple myeloma).
Protein Tests (e.g., Serum Protein Electrophoresis, Immunofixation) – Detect abnormal antibodies (M protein) in multiple myeloma.
Lactate Dehydrogenase (LDH) – Often elevated in aggressive lymphomas and leukemias.
Bone Marrow Aspiration – Removes liquid marrow for analysis of cell types and counts.
Bone Marrow Biopsy – Removes a small core of marrow to examine structure and infiltration by abnormal cells.
Karyotyping – Looks at chromosomes for structural abnormalities.
Fluorescence In Situ Hybridization (FISH) – Detects specific genetic changes linked to certain blood cancers.
Polymerase Chain Reaction (PCR) – Detects minimal residual disease and specific gene mutations.
Next-Generation Sequencing (NGS) – Profiles multiple cancer-related genes at once.
Flow Cytometry – Identifies specific cell surface markers to classify cancer type (e.g., B-cell vs. T-cell lymphoma).
Immunohistochemistry (IHC) – Detects proteins on cell surfaces or inside cells for diagnosis and classification.
X-rays – Detect bone damage (multiple myeloma).
CT Scan / MRI / PET Scan – Assess lymph node involvement, organ enlargement, or bone lesions.
Urine Protein Electrophoresis & Immunofixation – Detect light chains (Bence-Jones proteins) in multiple myeloma.
Useful guides
Explore resources for valuable insights into pathology and molecular testing. Access our collection of articles, case studies, and educational materials to enhance your understanding of our diagnostic solutions.
Breast cancer happens when cells in the breast grow and divide in an abnormal way, forming a lump or tumor. It can be non-invasive (stays in the ducts or lobules) or invasive (spreads into nearby tissue and possibly other parts of the body).
A lump or thickening in the breast or underarm
Changes in breast size or shape
Skin changes (redness, dimpling, puckering)
Nipple changes (inversion, discharge, or pain)
Persistent breast pain
Note: Many breast changes are not cancer, but any new symptom should be checked by a doctor.
Both women and men can develop breast cancer, though it is much more common in women.
Age (risk increases with age)
Family history of breast or ovarian cancer
Inherited genetic changes (like BRCA1/BRCA2)
Hormone replacement therapy
Lack of physical activity, obesity, alcohol use
Previous chest radiation
You can’t completely prevent it, but you can lower your risk by:
Staying physically active
Maintaining a healthy weight
Limiting alcohol
Not smoking
Talking to your doctor about screening and, if needed, genetic testing
Screening tests can find breast cancer early, often before symptoms appear. These include:
Mammogram (main screening test)
Ultrasound or MRI for higher-risk patients
Breast self-awareness (knowing your normal look and feel)
If something suspicious is found, your doctor may order:
Imaging tests (mammogram, ultrasound, MRI)
Biopsy (removing a small sample of tissue for lab testing)
Staging describes how large the tumor is and if it has spread. Stages range from 0 (non-invasive) to IV (spread to other parts of the body).
Treatment depends on the type and stage. Options include:
Surgery (lumpectomy or mastectomy)
Radiation therapy
Chemotherapy
Hormone therapy
Targeted therapy
Immunotherapy (for some cases)
Some chemotherapy drugs cause hair loss. Your care team can suggest ways to manage this, like wigs or scalp-cooling devices.
Many people work during treatment, but it depends on the treatment type, side effects, and your overall health.
It can recur, but your doctor will help you create a follow-up care plan to lower the risk and monitor for changes.
Local and online support groups
Counseling or therapy
Patient navigators and nonprofit cancer organizations
Friends and family support networks
Don’t wait. Contact your healthcare provider for an evaluation as soon as possible.