Gastrointestinal (GI) cancers
Delivering advanced gastrointestinal cancer solutions
for patients and their physicians.
for patients and their physicians.
Understanding gastrointestinal cancers
Gastrointestinal cancers occur when abnormal cells grow uncontrollably in the digestive tract or other organs in the abdomen. There are several types of GI cancers, and each type behaves differently and may require specific treatment approaches.
Types of gastrointestinal cancers
- Colorectal (colon and rectal) cancerColorectal cancer starts in the colon (large intestine) or rectum, which are the final parts of the digestive tract.Esophageal cancerEsophageal cancer develops in the esophagus, the muscular tube that carries food and liquids from the throat to the stomach.Hepatobiliary cancer (liver, bile ducts, gallbladder)These cancers arise in the liver, bile ducts, or gallbladder.Liver cancerLiver cancer usually refers to hepatocellular carcinoma (HCC), the most common type of primary liver cancer.Pancreatic cancerPancreatic cancer starts in the pancreas, an organ behind the stomach that helps with digestion and blood sugar regulation.Stomach cancerStomach cancer develops in the lining of the stomach and may grow slowly over time.Neuroendocrine cancer (digestive-related)These rare cancers develop from neuroendocrine cells in the digestive tract or pancreas.Common symptoms*Common symptoms affecting the digestive tract don’t always mean cancer. However, if you notice any of these symptoms consistently, it’s important to see a healthcare provider for evaluation.
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Abdominal pain or discomfort - Feeling full quickly after a small meal
- Heartburn or indigestion that persists
- Nausea or vomiting
- Poor appetite
- Unexplained weight loss
Test menu options for gastrointestinal cancers
Colorectal Cancer
5-gene panelColorectal Cancer
32-gene panelMost Types of Cancer
88-gene panelMMUNOTHERAPY BIOMARKERS: MSI, MMR, PD-L1505-gene panel + MSI & TMB for advanced solid tumorsLearn more about our testing optionsUseful guidesExplore resources for valuable insights into pathology and molecular testing. Access our collection of articles, case studies, and educational materials to enhance your understanding of our diagnostic solutions.FAQGI cancers are more common in men than women, and the risk increases with age, especially in people in their 60s, 70s, and 80s.Risk factors may include:- Being male
- Older age
- Certain ethnicities (Hispanic, African, Native American, Asian, Pacific Islander)
- Geography (higher rates in East Asia, Eastern Europe, South and Central America)
- Obesity, alcohol, or tobacco use
- Helicobacter pylori (H. pylori) infection
- Inherited cancer syndromes
While GI cancers can’t be completely prevented, you can lower your risk by:- Eating a healthy diet
- Maintaining a healthy weight and staying active
- Limiting alcohol and avoiding tobacco
- Treating H. pylori infections
- Discussing aspirin use with your doctor if appropriate
Doctors may use a combination of tests, including:- Endoscopy or esophagogastroduodenoscopy
- Colonoscopy
- Lab tests
- Imaging scans
- Biopsy
Treatment depends on the tumor’s location, size, and your health, and may include:- Surgery (if the tumor can be safely removed)
- Chemotherapy
- Radiation therapy
- Targeted therapy
- Immunotherapy
Some people continue working, but it depends on the treatment, side effects, and overall health.Yes, GI cancers can recur after treatment. Treatment for recurrence depends on location, prior therapies, and overall health.Support is available through:- Local and online support groups
- Counseling or therapy
- Patient navigators and nonprofit cancer organizations
- Friends and family networks
Don’t wait, contact your healthcare provider promptly for evaluation.*Note: Experiencing these symptoms does not always mean cancer. If you notice any of them, it’s important to speak with a healthcare provider for proper evaluation.References
- Living as a Gastrointestinal Neuroendocrine Tumor Survivor https://www.cancer.org/cancer/types/gastrointestinal-carcinoid-tumor/after-treatment/follow-up.html
- Stomach Cancer Recurrence https://www.moffitt.org/cancers/stomach-gastric-cancer/recurrence/
- Gastrointestinal Cancer Diagnosis https://utswmed.org/conditions-treatments/gastrointestinal-cancer/gastrointestinal-cancer-diagnosis/
- Gastrointestinal Cancers https://www.yalemedicine.org/conditions/gastrointestinal-cancers
- Gastrointestinal Cancers https://www.mountsinai.org/care/gastroenterology/services/gastrointestinal-cancer